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. 2020 Jan 7;34(6):591–599. doi: 10.1177/0269881119897559

Table 3.

Risk estimation based on 1747 ecstasy-related incidents reported to Monitor Drug Incidents (MDI) by 370,000 last year users of ecstasy (assuming a coverage by MDI of 33%), the Global Drug Survey survey (GDS, 2019), and 11 m last-year consumers of alcohol in the Netherlands (van Laar et al., 2019).

Type of incident Risk of a non-fatal incident
% Per user/per dose
Ecstasy-related incidents (MDI) a
All incidents per user 1.4 1 in 70 users
All incidents per pillb 0.3 1 in 340 pills
Moderate to severe incidents per pill 0.11 1 in 900 pills
Severe incidents per pillc 0.03 1 in 3400 pills
Severe incidents per user 0.14 1 in 700 users
Ecstasy-related incidents (GDS, 2019)d
Emergency medical treatment required 0.6 1 in 160 users
Emergency medical treatment required (per pill) 0.125 1 in 800 pills
Cocaine-related incidents (MDI) a
All incidents per user 0.45 1 in 215 users
All incidents per doseb 0.12 1 in 850 doses
Moderate to severe incidents per dose 0.06 1 in 1600 doses
Severe incidents per dose 0.02 1 in 6000 doses
GHB-related incidents (MDI) a
All incidents per user 3.5 1 in 270 users
All incidents per doseb 1.4 1 in 70 doses
Moderate to severe incidents per dose 1.05 1 in 95 doses
Severe incidents per dose 0.47 1 in 212 doses
Alcohol-related incidents e
Assistance of ED requiredf 0.15 1 in 650 users
Severe incidentsg 0.05 1 in 2000 users
Severe traffic accidentsh 0.03 1 in 3000 users

ED: emergency department; GHB: gamma-hydroxybutyrate; ICU: intensive care unit.

a

Putatively occurring nationwide, based on an estimated coverage by MDI of 33% of all incidents.

b

Based on median number of four sessions yearly, where 1.2 ecstasy pill is consumed per session; for cocaine: four sessions yearly; for GHB: 2.5 sessions yearly.

c

21% Of incidents are severe: the patient requires medical stabilisation at the ICU.

d

Dutch ecstasy users seeking emergency medical treatment in the last 12 months following ecstasy use (GDS, 2019).

e

Based on a total of 11 m drinkers in the Netherlands.

f

Some ED assistance was necessary in 17,800 alcohol-use-related accidents (van Laar et al., 2006).

g

In 2017, 6000 alcohol-related intoxications required treatment in the ED (van Laar et al., 2006).

h

Nearly 4000 severe alcohol-related traffic-related injuries required hospitalization.