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. 2020 May 25;21:372. doi: 10.1186/s12864-020-6767-x

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© The Author(s). 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — The expression profiles of genes. a PCA of 21-pair distinct samples across the seven ages based on normalized mRNAs expression level. The samples were grouped by age. The expression pattern of genes can be divided into three different clusters. The expression profiles of the samples at 90 dpp were separable from those at 0–60 dpp and 120–180 dpp. b Heat map of correlation coefficient for 21 samples based on the gene expression level. The samples were grouped by hierarchical clustering, and the dendrogram was not shown. Information of samples was shown in Additional file 8: Table S20. c Bar plot presentation of DEGs between neighboring age groups. d The Venn diagram shows the numbers of DEGs in D90 vs. D60 and D120 vs. D90. The total and overlay numbers of DEGs are 9098 and 747 respectively. The pie chart shows the changes in the common 747 DEGs