TABLE 1.
Summary of studied cohorts.
| Train set | Validation set 1 | Validation set 2 | |
| GEO access | GSE85217 | GSE85217 | GSE37418 |
| Microarray Platform | GPL22286 | GPL22286 | GPL570 |
| Cases included (n) | 371 | 160 | 70 |
| Age (mean ± SD) | 11.5 ± 9.2 | 11.7(±9.4) | 8.4(±3.12) |
| Overall survival | |||
| Year (mean ± SD) | 5.1 ± 3.7 | 5.1(±4.1) | 3.7(±1.8) |
| Status (alive/dead) | 278/93 | 118/42 | 58/12 |
| Gender | |||
| Female | 122 | 53 | 21 |
| Male | 179 | 104 | 49 |
| Histology | |||
| Classic | 206 | 107 | 48 |
| Des | 38 | 16 | 5 |
| LCA | 43 | 15 | 15 |
| MBEN | 5 | 0 | 2 |
| Subgroup | |||
| SHH | 84 | 37 | 10 |
| WNT | 43 | 19 | 8 |
| GROUP3 | 64 | 27 | 16 |
| GROUP4 | 180 | 77 | 34 |
GEO, Gene Expression Omnibus; SD, standard deviation; Des, desmoplastic/nodular; LCA, large-cell anaplastic; MBEN, medulloblastoma with extensive nodularity; SHH, sonic hedgehog; WNT, Wingless.