TABLE 2.
Gene signature selected for model construction.
| Probe | Gene | Coefficient | Factor | Expression level (high vs. low risk) |
| ENSG00000167740 | CYB5D2 | –0.244845303 | Protective | Decreased |
| ENSG00000188089 | PLA2G4E | –0.2109008 | Protective | Decreased |
| ENSG00000162458 | FBLIM1 | –0.199451582 | Protective | Decreased |
| ENSG00000104998 | IL27RA | –0.193108399 | Protective | Decreased |
| ENSG00000186838* | SELENOV | –0.168074864 | Protective | Decreased |
| ENSG00000231292 | IGKV1OR2-108 | –0.116666216 | Protective | Decreased |
| ENSG00000183914 | DNAH2 | –0.057694631 | Protective | Decreased |
| ENSG00000103888 | CEMIP | –0.054565913 | Protective | Decreased |
| ENSG00000180787 | ZFP3 | –0.021712839 | Protective | Decreased |
| ENSG00000275591 | XKR5 | –0.014694104 | Protective | Decreased |
| ENSG00000108100 | CCNY | 0.02622514 | Risk | Increased |
| ENSG00000107959 | PITRM1 | 0.104753688 | Risk | Increased |
| ENSG00000176438 | SYNE3 | 0.108748445 | Risk | Increased |
| ENSG00000004478 | FKBP4 | 0.196424875 | Risk | Increased |
*Excluded: no mapped gene in GLP570 platform. Gene names: Cytochrome B5 Domain Containing 2 (CYB5D2), Phospholipase A2 Group IVE (PLA2G4E), Filamin Binding LIM Protein 1 (FBLIM1), Interleukin 27 Receptor Subunit Alpha (IL27RA), Selenoprotein V (SELENOV), Immunoglobulin Kappa Variable 1/OR2-108 (IGKV1OR2-108), Dynein Axonemal Heavy Chain 2 (DNAH2), Cell Migration Inducing Hyaluronidase 1 (CEMIP), ZFP3 Zinc Finger Protein (ZFP3), XK Related 5 (XKR5), Cyclin Y (CCNY), Pitrilysin Metallopeptidase 1 (PITRM1), Spectrin Repeat Containing Nuclear Envelope Family Member 3 (SYNE3), and FKBP Prolyl Isomerase 4 (FKBP4).