Figure 3.

The number of publications per cancer type pertaining to CH variants in pediatric cancer. The literature on CH variants has covered a wide range of cancer types, especially acute lymphoblastic leukemia, non-Hodgkin's lymphoma, and medulloblastoma. In six publications, at least one patient was diagnosed with more than one cancer type. These “2+ diagnoses” include patients with the following cancer types: glioblastoma + non-Hodgkin's Lymphoma + oligodendroglioma (Bakry et al., 2014), glioblastoma + rectal carcinoma (Bakry et al., 2014), glioblastoma + non-Hodgkin's lymphoma (Chmara et al., 2013) or ALL + rectal adenoma (Herkert et al., 2011), acute myeloid leukemia + medulloblastoma (Scott et al., 2007), colon carcinoma + oligodendroglioma (De Rosa et al., 2000), brain tumor + rhabdomyosarcoma (Quesnel et al., 1999).