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MALDI-MSI of ATP in HT-29 spheroids with or without cetuximab treatments. (a) Ion images of ATP (m/z 506.0). (b) Average signal intensities of ATP from MALDI-MSI results (n = 6, *p < 0.05, **p < 0.01). (c) MALDI-MS/MS confirming that m/z 506.0 is the signal from ATP.
