Table 1.
Sequence-based motifs and frequency by population in N = 1036. Motifs are represented in this table if the motif frequency exceeds 1 % in at least one population. “All other motifs” is the sum frequency of all alleles not captured by a motif shown in the table. Variable stretches are denoted with “n”. Lower case letters are not counted toward the repeat number designation. Bolded values highlight examples of frequencies over 20 % higher in one population compared to all other populations.
| Locus | Frequency of Motif by Population |
||||||
|---|---|---|---|---|---|---|---|
| Allele Range | Motif | AfAm | Asian | Cauc | Hisp | ||
| D1S1656 | |||||||
| 10 to 18 | CCTA [TCTA]n | 46.35% | 66.49% | 50.69% | 52.54% | ||
| 10 to 17 | [TCTA]n | 31.14% | 17.01% | 15.51% | 17.58% | ||
| 14.3 to 19.3 | CCTA [TCTA]n TCA [TCTA]n | 21.78% | 15.98% | 31.99% | 28.18% | ||
| 15 to 17 | CTTA [TCTA]n | 0.29% | - | 0.97% | 1.27% | ||
| all other motifs | 0.44% | 0.52% | 0.83% | 0.42% | |||
| D2S441 | |||||||
| 8 to 13 | [TCTA]n | 53.80% | 56.19% | 41.55% | 34.96% | ||
| 12 to 17 | [TCTA]n TTTA [TCTA]2 | 32.02% | 10.82% | 32.96% | 27.75% | ||
| 10 to 13 | [TCTA]n TCTG TCTA | 8.19% | 18.04% | 16.20% | 27.75% | ||
| 11.3 to 14.3 | [TCTA]n TCA [TCTA]n | 5.26% | 3.61% | 6.51% | 4.66% | ||
| 10 to 12 | [TCTA]n rs74640515 | 0.58% | 10.82% | 2.63% | 4.87% | ||
| all other motifs | 0.15% | 0.52% | 0.14% | - | |||
| D2S1338 | |||||||
| 15 to 24 | [GGAA]n [GGCA]n | 55.99% | 51.03% | 57.89% | 58.05% | ||
| 19 to 27 | [GGAA]2 GGAC [GGAA]n [GGCA]n | 43.86% | 43.30% | 40.58% | 38.98% | ||
| 18 to 20 | [GGAA]n GAAA [GGAA]2 [GGCA]7 | - | 5.15% | - | 2.33% | ||
| 19 and 20 | [GGAA]n GGGA [GGCA]7 | - | 0.52% | 1.52% | 0.64% | ||
| all other motifs | 0.15% | - | - | - | |||
| D3S1358 | |||||||
| 12 to 18 | TCTA TCTG [TCTA]n | 42.40% | 3.61% | 5.26% | 9.53% | ||
| 11 to 20 | TCTA [TCTG]2 [TCTA]n | 33.33% | 71.13% | 59.28% | 59.96% | ||
| 14 to 20 | TCTA [TCTG]3 [TCTA]n | 23.54% | 24.74% | 34.90% | 30.08% | ||
| all other motifs | 0.73% | - | 0.55% | 0.42% | |||
| D4S2408 | |||||||
| 7 to 13 | [ATCT]n | 98.39% | 72.16% | 97.78% | 94.49% | ||
| 9 | ATCT GTCT [ATCT]7 | 1.32% | 27.84% | 2.22% | 5.51% | ||
| all other motifs | 0.29% | - | - | - | |||
| FGA | |||||||
| 17 to 29 | [GGAA]2 GGAG [AAAG]n AGAA AAAA [GAAA]3 | 89.33% | 98.97% | 97.51% | 97.25% | ||
| 22 to 30 | [GGAA]2 GGAG [AAAG]5 AAGG [AAAG]n AGAA AAAA [GAAA]3 | 6.29% | - | - | 1.48% | ||
| 16.2 to 25.2 | [GGAA]2 GGAG [AAAG]n --AA AAAA [GAAA]3 | 3.07% | 0.52% | 2.22% | 0.64% | ||
| all other motifs | 1.32% | 0.52% | - | 0.64% | |||
| D5S818 | |||||||
| 7 to 15 | [ATCT]n | 70.76% | 77.32% | 74.38% | 76.69% | ||
| 8 to 14 | [ATCT]n rs73801920 | 26.17% | 22.68% | 25.62% | 23.09% | ||
| 13 to 15 | [ATCT]3 ATGT [ATCT]n | 3.07% | - | - | 0.21% | ||
| all other motifs | - | - | - | - | |||
| D6S1043 | |||||||
| 8 to 15 | [ATCT]n | 54.82% | 61.86% | 69.25% | 64.41% | ||
| 15 to 22 | [ATCT]n ATGT [ATCT]n | 42.55% | 37.63% | 29.64% | 27.97% | ||
| 23 to 26 | [ATCT]n ATGT [ATCT]4 ATGT [ATCT]n | 1.90% | - | - | - | ||
| 18.3 to 23.3 | [ATCT]n ATGT [ATCT]2 ATC [ATCT]n | 0.44% | - | - | 6.99% | ||
| all other motifs | 0.29% | 0.52% | 1.10% | 0.64% | |||
| D7S820 | |||||||
| 6 to 14 | [TATC]n rs7789995 | 80.26% | 70.62% | 82.55% | 86.44% | ||
| 7 to 12 | [TATC]n rs7789995, rs16887642 | 17.40% | 24.74% | 5.96% | 4.87% | ||
| 9 to 14 | [TATC]n | 2.19% | 4.64% | 11.36% | 8.26% | ||
| all other motifs | 0.15% | - | 0.14% | 0.42% | |||
| D8S1179 | |||||||
| 8 to 16 | [TCTA]n | 16.67% | 50.52% | 46.26% | 37.50% | ||
| 11 to 17 | TCTA TCTG [TCTA]n | 38.89% | 26.29% | 41.69% | 42.37% | ||
| 11 to 18 | [TCTA]2 TCTG [TCTA]n | 41.08% | 23.20% | 11.36% | 19.07% | ||
| 13 to 18 | [TCTA]2 [TCTG]2 [TCTA]n | 3.07% | - | 0.14% | 0.21% | ||
| all other motifs | 0.29% | - | 0.55% | 0.85% | |||
| D9S1122 | |||||||
| 9 to 17 | [TAGA]n | 76.61% | 73.20% | 57.76% | 70.13% | ||
| 9 to 16 | TAGA TCGA [TAGA]n | 23.25% | 26.29% | 42.11% | 29.87% | ||
| all other motifs | - | - | - | - | |||
| vWA | |||||||
| 11 to 21 | [TAGA]n [CAGA]3–6 TAGA | 93.71% | 80.93% | 91.55% | 92.37% | ||
| 14 to 15 | [TGGA]0,1 [TAGA]3 TGGA [TAGA]3 [CAGA]4 TAGA CAGA TAGA rs75219269 | 3.36% | 19.07% | 8.17% | 7.42% | ||
| 14 to 15 | [TAGA]n [CAGA]4 TAGA rs771794429, rs199970098 | 1.90% | - | - | 0.21% | ||
| all other motifs | 1.02% | - | 0.14% | - | |||
| D12S391 | |||||||
| 14 to 27 | [AGAT]n [AGAC]n AGAT | 85.82% | 90.72% | 66.07% | 77.54% | ||
| 18 to 27 | [AGAT]n [AGAC]n | 10.96% | 7.73% | 27.70% | 18.22% | ||
| 17.3 to 19.3 | AGAT GAT [AGAT]n [AGAC]7 AGAT | 1.32% | - | 4.85% | 3.39% | ||
| 17.1 to 20.1 | AGAT T [AGAT]n [AGAC]6 AGAT | 1.75% | - | - | 0.21% | ||
| all other motifs | 0.15% | 1.55% | 1.39% | 0.64% | |||
| D13S317 | |||||||
| 8 to 15 | [TATC]n | 69.74% | 41.75% | 61.77% | 67.58% | ||
| 9 to 15 | [TATC]n rs9546005 | 28.36% | 54.12% | 35.46% | 29.66% | ||
| 10 and 11, 13 | [TATC]n rs9546005, rs202043589 | - | 3.09% | - | - | ||
| 11 and 12 | [TATC]n rs73250432, rs9546005 | - | 0.52% | 2.35% | 0.85% | ||
| 9 to 12 | [TATC]n rs9546005, rs561167308 | 1.02% | - | 0.14% | 0.64% | ||
| all other motifs | 0.88% | 0.52% | 0.28% | 1.27% | |||
| D16S539 | |||||||
| 8 to 15 | [GATA]n | 77.49% | 45.88% | 90.72% | 73.52% | ||
| 5, 9 to 14 | [GATA]n rs11642858 | 21.20% | 54.12% | 8.86% | 26.27% | ||
| 11 and 12 | [GATA]n rs114697632 | 1.17% | - | 0.28% | - | ||
| all other motifs | 0.15% | - | 0.14% | 0.21% | |||
| D18S51 | |||||||
| 9 to 24, 28 | [AGAA]n | 98.25% | 100.00% | 98.34% | 98.94% | ||
| 14, 15 | AGAA AGCA [AGAA]n | - | - | 1.39% | 0.21% | ||
| all other motifs | 1.75% | - | 0.28% | 0.85% | |||
| D19S433 | |||||||
| 9 to 17 | [CCTT]n ccta CCTT cttt CCTT | 73.25% | 68.56% | 90.86% | 81.14% | ||
| 12.2 to 18.2 | [CCTT]n ccta CCTT tt CCTT | 25.58% | 30.93% | 8.31% | 17.58% | ||
| all other motifs | 1.17% | 0.52% | 0.83% | 1.27% | |||
| D20S482 | |||||||
| 9 to 18 | [AGAT]n | 95.76% | 95.88% | 91.41% | 93.01% | ||
| 10 to 16, 19 | [AGAT]n rs77560248 | 4.24% | 3.61% | 8.59% | 6.99% | ||
| all other motifs | - | 0.52% | - | - | |||
| D21S11 | |||||||
| 26 to 39 | [TCTA]n [TCTG]n [TCTA]n ta [TCTA]n tca [TCTA]2 tccata [TCTA]n | 81.29% | 78.35% | 74.52% | 70.76% | ||
| 28.2 to 34.2 | [TCTA]n [TCTG]n [TCTA]3 ta [TCTA]n tca [TCTA]2 tccata [TCTA]n TA TCTA | 16.52% | 20.62% | 25.07% | 28.60% | ||
| 35, 36 | [TCTA]5 [TCTG]6 [TCTA]3 ta [TCTA]3 tca [TCTA]2 tccata [TCTA]n TCA [TCTA]3 TCA [TCTA]2 TA TCTA | 1.75% | - | 0.14% | - | ||
| 29.3, 30.3 | [TCTA]n [TCTG]n [TCTA]3 ta [TCTA]3 tca [TCTA]2 tccata [TCTA]n TCA [TCTA]n | 0.15% | 1.03% | - | - | ||
| all other motifs | 0.29% | - | 0.28% | 0.64% | |||
| Penta D | |||||||
| 5 to 17 | [AAAGA]n | 85.96% | 99.48% | 99.03% | 97.45% | ||
| 2.2, 3.2 | [AAAGA]n rs1190908807 | 12.28% | - | 0.42% | 1.91% | ||
| all other motifs | 1.75% | 0.52% | 0.55% | 0.64% | |||