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. 2020 May 19;11:737. doi: 10.3389/fphar.2020.00737

Figure 1.

Figure 1

CCT020312 suppressed TNBC cell viability in vitro. (A) The chemical structure of CCT020312. (B, C) MDA-MB-453 cells (B) and CAL-148 cells (C) were treated with CCT020312 at different doses for 24 or 48 h. Cell viability was measured with CCK-8 (n = 5). (D, E) MDA-MB-453 cells (D) and CAL-148 cells (E) were treated with CCT020312 at different doses, cell growth curve assays were performed using real-time cell analysis by xCELLigence (n = 3). (F) CAL-148 cells were treated with various of CCT020312 for 12 days, and the surviving colonies were stained with crystal violet. Colonies with more than 50 cells were counted under an inverted microscope (n = 3). Data are presented as mean ± SD, *p < 0.05 or **p < 0.01 vs. control.