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. 2020 May 19;11:737. doi: 10.3389/fphar.2020.00737

Figure 2.

Figure 2

CCT020312 induced the apoptosis of TNBC cells. (A, B) MDA-MB-453 cells (A) and CAL-148 cells (B) were treated with CCT020312 at different concentrations for 24 h. Flow cytometry was used to detect apoptosis (n = 3). Data are presented as mean ± SD, *p < 0.05 or **p < 0.01 vs. control. (C, D) MDA-MB-453 cells (C) and CAL-148 cells (D) were treated with various of CCT020312 for 24 h, or treated with 8 and 10 μM CCT020312 for indicated time, then cells were collected to detect cleaved PARP, Bax, and Bcl-2 level using Western blotting.