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. Author manuscript; available in PMC: 2021 Mar 11.
Published in final edited form as: Environ Sci Process Impacts. 2020 Mar 11;22(3):824–832. doi: 10.1039/c9em00597h

Figure 3. TCE effects on identified HNF4a and TCE markers in mouse embryo hearts.

Figure 3.

HBEGF and INSR are known targets of HNF4a activity while the remaining markers tested were chosen from among the most significantly affected genes in a microarray analysis of exposure in the developing chick heart. All markers were significantly downregulated by exposure to TCE in utero. Data show the average and SEM of the three litters exposed to 10ppb TCE and are normalized to the average measure of each primer pair with three untreated control litters. All transcriptional changes were significant as evaluated by Student’s T Test (unpaired, two-tailed). *p>.05, **p>.005.