Table 3.
Relative Changes (% from Pre-Exercise Levels) in Mediators of Inflammation After Various Types of Exertion
| Marathon Run | Half-Marathon Run | 24-h Skiing | |
|---|---|---|---|
| Calprotectin | +342 | +304 | +1427 |
| suPAR | +53 | +20 | +51 |
| CD163 | +71 * | +9 | +4 |
| IL-6 | +687 | +561 | +2178 |
| IL-8 | +252 ** | +18 | +251 |
| IL-10 | +228 | +95 | +40 |
| TNF-α | +160 ** | –28 | +140 |
| TGF-β | –24 | –3 | +721 |
| Leukocytes | +128 | +148 | +132 |
Notes: Relative change significantly different between marathon run and half-marathon run (Mann–Whitney U-test), *p < 0.05, **p < 0.01.
Abbreviations: suPAR, soluble urokinase plasminogen activator receptor, a biomarker of immune activation; CD163, a biomarker of monocyte-macrophage activation; IL, interleukin; TNF-α, tumor necrosis factor-alpha; TGF-β, transforming growth factor-beta.