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. 2020 May 22;13:4533–4544. doi: 10.2147/OTT.S244358

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© 2020 Wang et al.

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Circ_0001023/miR-409-3p axis regulates the apoptosis of GC cells. (A) Transwell assay confirmed that overexpressed circ_0001023 promoted the migration of AGS cells, which was partially reversed by miR-409-3p mimics. Knockdown of circ_0001023 inhibited the migration of GC cells, and miR-409-3p inhibitors partially reversed it. (B) Transwell assay validated that overexpressed circ_0001023 facilitated the invasion of AGS cells, and miR-409-3p mimics showed inhibitory effect. Knockdown of circ_0001023 can impede the invasion of GC cells, and miR-409-3p inhibitors partially weaken it. *** and *** represent p<0.05, p<0.01 and p< 0.001, respectively. # and ## represent p<0.05 and p<0.01, respectively.