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. 2019 Dec 11;6(3):210–218. doi: 10.1159/000504312

Table 3.

2018 practice patterns as determined by survey responses

ABS, TG 129 Institution
A B C D E F G H I
Planning program FDA approved software Eye physics plaque simulator Pinnacle and eye physics plaque simulator Eye physics plaque simulator Eye physics plaque simulator Eye physics plaque simulator Eye physics plaque simulator Eye physics plaque simulator Varian eclipse brachyvision Eye physics plaque simulator

Year changed to current method 2016 2013 2015 2016 2015 2013 1995 2013 2017

Imaging Fundus image, ultrasonographs, and/or CT and MRI Fundus image Fundus image and CT Fundus image ± CT/MRI Fundus image CT Fundus image and OCT Fundus image and CT Ultrasound Fundus image AND ultrasound AND CT

Fundus camera Not reported Wide field Wide field and standard Standard Wide field and standard Wide field and standard Wide field

Plaque style Eye physics Eye physics COMS style COMS style Eye physics COMS style Eye physics COMS style Eye physics and COMS style

Who chooses plaque size Not reported Ophthalmology Ophthalmology Ophthalmology Medical physics Ophthalmology and radiation Oncology Medical physics Ophthalmology Ophthalmology

Plaque margin, mm 2–3 mm 3.27±1.00 (1.15–6.17) 3.62±1.02 (0.75–5.5) 2.42±0.40 (1.75–3.35) 3.40±1.00 (2–6.4) 2.34±1.46 (–2–3.5) 2.24±0.97 (0–7.7) 4.08±1.63 (0.29–5.53) 2.6±0.7 (1–3.6) 2.3±0.3 (1.6–3.3)

Margin no notch, mm 3.13 ±0.91 (1.15–6.17) 3.38±0.90 (0.75–4.5) 2.38±0.37 (1.75–3.2) 3.27±0.86 (2–5.3) 1.69±1.67 (–2–3.5) 2.27±1.01 (1–7.7) 3.52±2.05 (0.29–5.41) 2.6±0.7 (1–3.3) 2.3±0.3 (1.6–3.3)

Margin notch, mm 3.64±1.15 (2–5.75) 4.13±1.05 (2.25–5.5) 2.56±0.54 (2.15–3.35) 4.49±1.50 (2.7–6.4) 2.82±1.15 (2–5) 2.14±0.79 (0–3.5) 4.63±1.00 (3.04–5.53) 2.6±0.7 (1.5–3.6) 2.6±0.1 (2.5–2.8)

Plaque loading Pre-loaded Pre-loaded Pre-loaded In house Pre-loaded Pre-loaded Pre-loaded Pre-loaded Pre-loaded

Isotope I-125 I-125 I-125 I-125 I-125 I-125 I-125 I-126 I-127

Seed uniformity Uniform Uniform Primarily uniform, 2 activities if needed for sparing or coverage Primarily uniform, 2 activities if needed for sparing or coverage Uniform Uniform Variable Uniform Uniform

Duration, h 96 168 72 100 96 100 168 120–168 89–96

Prescription dose, Gy 85 63 85 85, 75–80 to spare sclera 85 85 85 85 85 85

Dose rate, cGy/h 60–105a 66 51 118 85 89 85 51 50 88–100

Prescription point Tumor apex Tumor apex, add height to achieve coverage as needed ≥5 mm: tumor apex, <5 mm: 5 mm from inner sclera Tumor apex ±1 mm, short tumors: beyond apex ≥5 mm: tumor apex, <5 mm: 1 mm beyond apex ≥5 mm: tumor apex, <5 mm: tumor apex + margin Tumor apex, add height to achieve coverage as needed ≥5 mm: tumor apex, <5 mm: tumor apex + margin ≥5 mm: tumor apex, <5 mm: tumor apex + margin ≥3.5 mm: Tumor apex, <3.5 mm: 3.5 mm

Normal tissue constraints None None Optic disc Dmax <45 Gy, macula Dmax <45 Gy Sclera Dmax <400 Gy Optic disc Dmax <50 Gy, macula Dmax <50 Gy None None None None

General corrections Linear source model Linear source model, 2-D anistropy function Linear source model, 2-D anistropy function, air scatter correction Linear source model, 2-D anistropy function Linear source model, 2-D anistropy function, air scatter correction Linear source model, 2-D anistropy function None Linear source model, 2-D anistropy function None Linear source model, 2-D anistropy function, air scatter correction

COMS corrections Homogeneous water AND silastic carrier attenuation, lipped collimation, and shell collimationb Silastic carrier attenuation, lipped collimation, shell collimation Silastic carrier attenuation, lipped collimation, shell collimation Silastic carrier attenuation, lipped collimation, shell collimation Silastic carrier attentuation, lipped collimation, shell collimation

Eye physics corrections Gold correction, slotted collimation Gold correction, slotted collimation Gold correction, slotted collimation Slotted collimation Gold correction, slotted collimation Gold correction, slotted collimation

CT, computed tomography; COMS, Collaborative Ocular Melanoma Study.

a

American Brachytherapy Society (ABS) dose rate recommendation is ≥60 cGy/h; American Association of Physicists in Medicine Task Group-43 (TG-43) recommendation is 42–105 cGy/h.

b

It is recommended by the ABS and AAPM to use homogenous water for dose calculation but to simultaneously calculate heterogeneity corrected doses for comparison.