Table 3.
2018 practice patterns as determined by survey responses
ABS, TG 129 | Institution |
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---|---|---|---|---|---|---|---|---|---|---|
A | B | C | D | E | F | G | H | I | ||
Planning program | FDA approved software | Eye physics plaque simulator | Pinnacle and eye physics plaque simulator | Eye physics plaque simulator | Eye physics plaque simulator | Eye physics plaque simulator | Eye physics plaque simulator | Eye physics plaque simulator | Varian eclipse brachyvision | Eye physics plaque simulator |
Year changed to current method | 2016 | 2013 | 2015 | 2016 | 2015 | 2013 | 1995 | 2013 | 2017 | |
Imaging | Fundus image, ultrasonographs, and/or CT and MRI | Fundus image | Fundus image and CT | Fundus image ± CT/MRI | Fundus image | CT | Fundus image and OCT | Fundus image and CT | Ultrasound | Fundus image AND ultrasound AND CT |
Fundus camera | Not reported | Wide field | Wide field and standard | Standard | Wide field and standard | Wide field and standard | Wide field | |||
Plaque style | Eye physics | Eye physics | COMS style | COMS style | Eye physics | COMS style | Eye physics | COMS style | Eye physics and COMS style | |
Who chooses plaque size | Not reported | Ophthalmology | Ophthalmology | Ophthalmology | Medical physics | Ophthalmology and radiation Oncology | Medical physics | Ophthalmology | Ophthalmology | |
Plaque margin, mm | 2–3 mm | 3.27±1.00 (1.15–6.17) | 3.62±1.02 (0.75–5.5) | 2.42±0.40 (1.75–3.35) | 3.40±1.00 (2–6.4) | 2.34±1.46 (–2–3.5) | 2.24±0.97 (0–7.7) | 4.08±1.63 (0.29–5.53) | 2.6±0.7 (1–3.6) | 2.3±0.3 (1.6–3.3) |
Margin no notch, mm | 3.13 ±0.91 (1.15–6.17) | 3.38±0.90 (0.75–4.5) | 2.38±0.37 (1.75–3.2) | 3.27±0.86 (2–5.3) | 1.69±1.67 (–2–3.5) | 2.27±1.01 (1–7.7) | 3.52±2.05 (0.29–5.41) | 2.6±0.7 (1–3.3) | 2.3±0.3 (1.6–3.3) | |
Margin notch, mm | 3.64±1.15 (2–5.75) | 4.13±1.05 (2.25–5.5) | 2.56±0.54 (2.15–3.35) | 4.49±1.50 (2.7–6.4) | 2.82±1.15 (2–5) | 2.14±0.79 (0–3.5) | 4.63±1.00 (3.04–5.53) | 2.6±0.7 (1.5–3.6) | 2.6±0.1 (2.5–2.8) | |
Plaque loading | Pre-loaded | Pre-loaded | Pre-loaded | In house | Pre-loaded | Pre-loaded | Pre-loaded | Pre-loaded | Pre-loaded | |
Isotope | I-125 | I-125 | I-125 | I-125 | I-125 | I-125 | I-125 | I-126 | I-127 | |
Seed uniformity | Uniform | Uniform | Primarily uniform, 2 activities if needed for sparing or coverage | Primarily uniform, 2 activities if needed for sparing or coverage | Uniform | Uniform | Variable | Uniform | Uniform | |
Duration, h | 96 | 168 | 72 | 100 | 96 | 100 | 168 | 120–168 | 89–96 | |
Prescription dose, Gy | 85 | 63 | 85 | 85, 75–80 to spare sclera | 85 | 85 | 85 | 85 | 85 | 85 |
Dose rate, cGy/h | 60–105a | 66 | 51 | 118 | 85 | 89 | 85 | 51 | 50 | 88–100 |
Prescription point | Tumor apex | Tumor apex, add height to achieve coverage as needed | ≥5 mm: tumor apex, <5 mm: 5 mm from inner sclera | Tumor apex ±1 mm, short tumors: beyond apex | ≥5 mm: tumor apex, <5 mm: 1 mm beyond apex | ≥5 mm: tumor apex, <5 mm: tumor apex + margin | Tumor apex, add height to achieve coverage as needed | ≥5 mm: tumor apex, <5 mm: tumor apex + margin | ≥5 mm: tumor apex, <5 mm: tumor apex + margin | ≥3.5 mm: Tumor apex, <3.5 mm: 3.5 mm |
Normal tissue constraints | None | None | Optic disc Dmax <45 Gy, macula Dmax <45 Gy | Sclera Dmax <400 Gy | Optic disc Dmax <50 Gy, macula Dmax <50 Gy | None | None | None | None | |
General corrections | Linear source model | Linear source model, 2-D anistropy function | Linear source model, 2-D anistropy function, air scatter correction | Linear source model, 2-D anistropy function | Linear source model, 2-D anistropy function, air scatter correction | Linear source model, 2-D anistropy function | None | Linear source model, 2-D anistropy function | None | Linear source model, 2-D anistropy function, air scatter correction |
COMS corrections | Homogeneous water AND silastic carrier attenuation, lipped collimation, and shell collimationb | Silastic carrier attenuation, lipped collimation, shell collimation | Silastic carrier attenuation, lipped collimation, shell collimation | Silastic carrier attenuation, lipped collimation, shell collimation | Silastic carrier attentuation, lipped collimation, shell collimation | |||||
Eye physics corrections | Gold correction, slotted collimation | Gold correction, slotted collimation | Gold correction, slotted collimation | Slotted collimation | Gold correction, slotted collimation | Gold correction, slotted collimation |
CT, computed tomography; COMS, Collaborative Ocular Melanoma Study.
American Brachytherapy Society (ABS) dose rate recommendation is ≥60 cGy/h; American Association of Physicists in Medicine Task Group-43 (TG-43) recommendation is 42–105 cGy/h.
It is recommended by the ABS and AAPM to use homogenous water for dose calculation but to simultaneously calculate heterogeneity corrected doses for comparison.