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. 2020 May 8;11:655. doi: 10.3389/fphar.2020.00655

Table 1.

Current anti-TNF-α available treatments in non-infectious uveitis.

Therapy Description Study type References
Adalimumab Anti TNF-α humanized antibody Clinical trial (Diaz-Llopis et al., 2008)
Systematic review (Borrás-Blasco et al., 2015)
Clinical trial (Jaffe et al., 2016)
Clinical trial (Goto et al., 2019)
Prospective study (Sharma et al., 2019)
Meta-analysis (Leal et al., 2019)
Systematic review (Leal et al., 2018)
Clinical trial (Suhler et al., 2018)
Clinical trial (Lee et al., 2018)
Retrospective study (Mercier et al., 2018)
Clinical trial (Nguyen et al., 2016)
Infliximab Anti TNF-α chimeric antibody Systematic review (Borrás-Blasco et al., 2015)
Prospective study (Sharma et al., 2019)
Meta-analysis (Leal et al., 2019)
Systematic review (Leal et al., 2018)
Retrospective study (Mercier et al., 2018)
Golimumab Anti TNF-α humanized antibody Systematic review (Borrás-Blasco et al., 2015)
Meta-analysis (Leal et al., 2019)
Systematic review (Leal et al., 2018)
Etanercept Anti TNF-α dimeric protein, act as a decoy for TNF-α Receptor Meta-analysis (Leal et al., 2019)
Systematic review (Leal et al., 2018)
Certolizumab Anti TNF-α antibody Systematic review (Leal et al., 2019)
Systematic review (Leal et al., 2018)

TNF-α, tumor necrosis factor alpha.