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. 2020 Mar 20;12(5):535–552. doi: 10.1093/gbe/evaa055

Table 1.

Aeromonad Virulence Factors Studied

Virulence Factor Reference Sequences
Virulence-Associated Gene Genomic Location Source
Accession No. Strain Length (Amino Acids)
Aerolysin AerA (syn: Cytolytic enterotoxin Act)
  • bestiarum Ah65

  • A. dhakensis SSU

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493493 aer (syn: act) Chromosome Howard et al. (1987), Chakraborty et al. (1987), Chopra et al. (1993)
Thermolabile cytotonic enterotoxin Q44061E A. dhakensis SSU 368 alt Chromosome Chopra et al. (1996)
Thermostable cytotonic enterotoxin Q8VRN3E A. dhakensis SSU 636 ast Chromosome Sha et al. (2002)
Extracellular collagenase J7FWV3E A. piscicola AH-3 915 colAh Chromosome Duarte et al. (2015)
Toxin RtxA (repeat-in-toxin A) A0KHZ7E A. hydrophila subsp. hydrophila ATCC 7966T 4,685 rtxA Chromosome Suarez et al. (2012)
Exotoxin A A0A0W0AX19E A. salmonicida Y577 639 exoA Unknown (chromosome in P. aeruginosa PA01) Tsaur and Clowes (1989), Ponnusamy et al. (2016), Vincent et al. (2016)
SST3 needle protein AscF Q6WG33E A. veronii 283c 85 ascF Chromosome or plasmid (chromosome in A. hydrophila ANNIH1 and ALO6-06/ plasmid in A. salmonicida subsp. salmonicida A449) Chacon et al. (2004), Reith et al. (2008); Tekedar et al. (2015),Hughes et al. (2016)
SST3 component AscG Q6WG32E A. veronii 283c 116 ascG
SST3 Inner membrane channel protein AscV A4SUH2E A. salmonicida subsp. salmonicida A449 721 ascV
ADP-ribosyltransferase toxin AexT Q93Q17S A. salmonicida subsp. salmonicida A449 475 aexT Chromosome Stuber et al. (2003), Dacanay et al. (2006), Reith et al. (2008), Silver and Graf (2009)
ADP-ribosyltransferase toxin AexU D5LUP3E A. veronii bv. sobria AeG1 512 aexU Chromosome Sha et al. (2007), Silver and Graf (2009), Abolghait et al. (2011)
Lateral flagellin A Q93TL9E A. caviae Sch3 281 lafA Chromosome Kirov et al. (2002), Canals et al. (2006)
Serine protease Ahe2 A4SNU7E A. salmonicida subsp. salmonicida A449 625 ser (syn.: ahe2) Chromosome Reith et al. (2008)

Note.—S/E, accession numbers correspond to protein sequences in SwissProt or TrEMBL databases.