Table 3.
Comparison of Impact of Event Scale, Multidimensional Impact of Cancer Risk Assessment, and Satisfaction with Decision Instrument Scores between Sub-Groups
CA/mutation + (n = 11) | CA/VUS (n = 14) | CA/mutation − (n = 104) | No CA/mutation + (n = 14) | No CA/VUS (n = 20) | No CA/mutation − (n = 69) | Non-parametric group comparison (p) | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | Mean (sd) Median (IQR) | n | Mean (sd) Median (IQR) | n | Mean (sd) Median (IQR) | n | Mean (sd) Median (IQR) | n | Mean (sd) Median (IQR) | n | Mean (sd) Median (IQR) | ||
IES, total | 11 | 6.8 (12) 2 (0, 6) | 13 | 7.6 (9.9) 3 (2, 10) | 100 | 8.0 (15) 1 (0, 11) | 14 | 18.1 (12) 17 (8, 24) | 18 | 8.8 (11) 3.5 (1, 14) | 66 | 6.7 (11) 1 (0, 11) | 0.01 |
IES, intrusion | 11 | .2 (.4) 0 (0, 0.1) | 13 | .3 (.4) 0.1 (0, 0.5) | 99 | .3 (.7) 0 (0, 0.4) | 14 | 1 (.8) 0.7 (0.5, 1.6) | 18 | .4 (.5) 0.3 (0, 0.5) | 66 | .3 (.5) 0 (0, 0.5) | 0.0009 |
IES, avoidance | 11 | .4 (.7) 0 (0, 0.8) | 13 | .5 (.7) 0.3 (0.1, 0.5) | 100 | .5 (.9) 0 (0, 0.6) | 14 | 1 (.6) 1.0 (0.5, 1.5) | 18 | .5 (.6) 0.3 (0, 1.1) | 66 | .4 (.7) 0 (0, 0.5) | 0.01 |
IES, hyperarousal | 11 | .3 (.6) 0 (0, 0.2) | 13 | .2 (.3) 0 (0, 0.2) | 100 | .3 (.7) 0 (0, 0.2) | 14 | .5 (.7) 0.2 (0.2, 0.7) | 18 | .2 (.4) 0 (0, 0.2) | 66 | .2 (.4) 0 (0, 0.2) | 0.07 |
MICRA, total | 11 | 19.4 (12.2) 19 (10, 26) | 13 | 12.4 (8.6) 14 (3, 18) | 100 | 11.6 (9.4) 10 (3, 18) | 13 | 29.6 (14.0) 25 (22, 42) | 17 | 19.0 (10.8) 18 (11, 22) | 67 | 12.4 (8.6) 12 (5, 20) | 0.0001 |
MICRA, distress | 11 | 4.5 (6.7) 0 (0, 9) | 12 | 3.3 (3.7) 3 (0, 6) | 99 | 1.4 (3.1) 0 (0, 1) | 13 | 10.9 (5.7) 9 (8, 13) | 17 | 3.3 (5.8) 0 (0, 1) | 69 | 1.5 (3.1) 0 (0, 3) | 0.0001 |
MICRA, uncertainty | 11 | 3.9 (4.2) 2 (0, 8) | 13 | 4.8 (5.3) 4 (0, 6) | 99 | 4.2 (5.2) 3 (0, 6) | 13 | 9.6 (7.7) 6 (3, 15) | 17 | 6.0 (7.3) 3 (2, 7) | 67 | 4.3 (5.3) 3 (0, 7) | 0.13 |
MICRA, positive experience | 11 | 10.9 (5.5) 10 (7, 16) | 13 | 4.7 (3.5) 4 (2, 6) | 100 | 6.1 (6.7) 4 (0, 10) | 13 | 9.1 (4.6) 10 (6, 11) | 17 | 9.7 (7.1) 10 (3, 16) | 67 | 6.6 (7.3) 4 (0, 12) | 0.03 |
SWD | 11 | 20.5 (6.2) 22 (20, 25) | 13 | 21.5 (5.6) 25 (20, 25) | 100 | 20.9 (5.9) 23 (20, 25) | 14 | 21.7 (3.3) 21 (20, 25) | 18 | 23.1 (2.2) 25 (21, 25) | 66 | 22.2 (4.2) 25 (20, 25) | 0.80 |
IES: Impact of Event Scale; MICRA: Multidimensional Impact of Cancer Risk Assessment; SWD: Satisfaction with Decision Instrument