. Author manuscript; available in PMC: 2021 Jun 2.

Published in final edited form as: Angew Chem Int Ed Engl. 2020 Mar 24;59(23):9143–9148. doi: 10.1002/anie.202001824

Table 1.

Optimization of reaction conditions^a


entry	deviation from standard	GC yield (%)^a,b
1	none	63
2	PC-2 instead of PC-1	11
3	PC-3 instead of PC-1	0
4	Az-2 instead of Az-1	14
5	Az-3 instead of Az-1	0
6	Az-4 instead of Az-1	0
7	Az-5 instead of Az-1	11
8	CsOAc instead of Cs₂CO₃	38
9	K₂CO₃ instead of Cs₂CO₃	8
10	Li₂CO₃ instead of Cs₂CO₃	0
11	CH₃CN instead of THF	72
12	CH₂CI₂ instead of THF	41
13	DMF instead of THF	65
14	no light	0
15	no photocatalyst	0
16	no Az	0
17	no base	0

Gas chromatography (GC) yield is based on a calibration curve using 1,3,5-trimethoxybenzene as the internal standard.

Reaction conditions: 1a (0.10 mmol), Bn–HE 2a (0.15 mmol), Az (0.015 mmol), base (0.015 mmol), PC (1 μmol), solvent (0.1 M; THF, tetrahydrofuran; DMF, dimethyformamide) for 16 h.