Table 3.
COVID-19 outbreak intervention: Altered fractionation schedules
| Initial fractionation schedule | n | Modified fractionation schedule | n | |
|---|---|---|---|---|
| Breast | WBRT: 50 Gy/25fr 5fr/wk + boost: 16 Gy/8 fr and RNI: 46Gy/23 fr | 3 | WBRT and RNI: 45 Gy/18 fr, 4 fr/wk + boost: 15 Gy/6 fr, 4 fr/wk | 3 |
| WBRT: 50 Gy/25fr + boost: 10 Gy/4 fr and RNI: 46 Gy/23 fr | 1 | WBRT and RNI: 45 Gy in 18 fr, 4 fr/wk + boost: 15 Gy/6 fr, 4 fr/wk | 1 | |
| WBRT (reconstructed): 50.4 Gy/28fr + boost: 16 Gy/8 fr | 4 | WBRT: 50.4 Gy/28 fr + boost: 15 Gy/6 fr, 4fr/wk Altered boost fractionation only |
1 | |
| WBRT: 50.4 Gy/28 fr + boost: 12 Gy/4fr, 3 fr/wk Altered boost fractionation only |
2 | |||
| WBRT: 50,4 Gy/28 fr + boost: 10 Gy/4 fr, 4 fr/wk | 1 | |||
| WBRT: 50 Gy/25fr + boost: 16 Gy/8 fr | 12 | WBRT: 50 Gy/25 fr + boost: 15 Gy/6 fr, 4 fr/wk Altered boost fractionation only |
1 | |
| WBRT: 50 Gy/25 fr + boost: 1 2Gy/4 fr, 3 fr/wk Altered boost fractionation only |
1 | |||
| WBRT: 45 Gy/18 fr, 4 fr/wk + boost: 15Gy in 6 fr, 4 fr/wk | 5 | |||
| WBRT: 45 Gy/18 fr, 4 fr/wk + boost: 10 Gy in 4 fr, 4 fr/wk | 3 | |||
| WBRT: 40 Gy/15 fr + boost: 10 Gy in 4 fr, 4 fr/wk | 2 | |||
| WBRT: 50 Gy/25 fr + boost: 10Gy/ 4 fr | 1 | WBRT: 45 Gy/20 fr, 4 fr week + boost: 10 Gy/4 fr, 4 fr/wk | 1 | |
| Skin | WBRT: 45 Gy/15 fractions, 3 fr/wk | 2 | 30 Gy in 5 fr, 1 fr week, 6 Gy per 1 fr | 1 |
| 36 Gy/12 fr | 1 | |||
| Sarcoma | TB: 50Gy/25 fr + boost: 10Gy/5 fr, | 1 | TB: 50Gy in 20 fr, 4 fr/wk + boost: 10Gy/4 fr, 4fr/wk | 1 |
| High-grade Lymphoma |
40Gy/20 fr, 5fr /wk | 1 | 36Gy/12 fr, 4 fr/wk | 1 |
| Bone metastases | 20Gy/5 fr, 5 fr/wk | 1 | 20Gy/4 fr, 4 fr/wk | 1 |
Abbreviations: COVID-19 = coronavirus disease 2019; WBRT = whole-breast radiation therapy; RNI = regional nodal irradiation; fr = fractions; TB = tumor bed.