Figure 1.

Representation of the MBT-derived Rvfs2 region in the congenic C.MBT-Rvfs2 strain and its effect on mouse survival. (A) Haplotype structure of the congenic segment of Chr 11 in C.MBT-Rvfs2 strain. The MBT-derived segment is depicted in white on the BALB/cByJ Chr 11 background (black). Regions of unknown genotype are depicted in grey. Markers are SNPs from the GigaMUGA array (see Table S2 from³⁷) and position are given in bp from mouse Genome Build 38 (corrected from¹⁹). (B) Survival curves of C.MBT-Rvfs2 and BALB male mice infected with 100 PFU IP (Mantel-Cox’s Logrank test; p < 0.0001).