Figure 2.
Clinical traits and biochemical parameters of RVFV-infected C.MBT-Rvfs2 and BALB mice. (A) Body weight variation in C.MBT-Rvfs2 (Rvfs2) and BALB mice after infection with RVFV ZH548 (mean ± SEM). (B) Body temperature variation in C.MBT-Rvfs2 and BALB mice during the days preceding the death (mean ± SEM). No difference was observed between the two strains (two-way ANOVA, p = 0.69). (C,D) Alanine aminotransferase (ALT) (C), and aspartate aminotransferase (AST) (D) levels in the serum of C.MBT-Rvfs2 and BALB mice. By day 5 p.i., all C.MBT-Rvfs2 mice had died. Data are means ± SEM for N = 4-9 mice per day, except for day 8 in BALB mice where N = 1.