Table 2.
Univariate and multivariate logistic regression analysis for persistent AKI.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Log uNGAL | 1.83 (1.67,2.06) | <0.001 | 1.72 (1.42,2.08) | <0.001 |
| Log uNGAL-Cr | 1.71 (1.54,1.91) | <0.001 | ||
| ICU vs other wards | 1.36 (0.99,1.87) | 0.06 | 2.09 (1.08,4.04) | 0.03 |
| AKI stage | ||||
| 1 | Reference | 0.001 | Reference | 0.10 |
| 2 | 1.73 (1.25,2.39) | <0.001 | 1.69 (0.90,3.20) | 0.003 |
| 3 | 7.23 (5.02,10.43) | 3.21 (1.50,6.85) | ||
| Sepsis | 1.63 (1.24,2.15) | <0.001 | 0.96 (0.50,1.82) | 0.90 |
| Ischemic cause | 0.56 (0.43,0.73) | <0.001 | 0.68 (0.36,1.28) | 0.23 |
| CKD | 1.89 (1.43,2.49) | <0.001 | 1.38 (0.73,2.62) | 0.33 |
| Cr at AKI diagnosis | 1.47 (1.31,1.66) | <0.001 | 2.23 (1.50,3.32) | <0.001 |
| FENa | 1.17 (1.08,1.26) | <0.001 | 1.17 (1.03,1.32) | 0.01 |
| FEuric | 1.04 (1.02,1.06) | <0.001 | 1.01 (0.98,1.03) | 0.69 |
Abbreviations OR, odds ratio; CI, confidence interval; uNGAL, urine neutrophil gelatinase-associated lipocalin; FENa, fractional excretion of sodium; FEuric, fractional excretion of uric; Cr, creatinine; CKD, chronic kidney disease.