Table 2.
CPH model of the effect of 5XUPRE levels on neuronal survival adjusted by groups (Ch and G93ASOD1Ch).
| 24 h | 48 h | 72 h | 96 h | |
|---|---|---|---|---|
| n | 523 | 405 | 365 | 329 |
| HR Q1 (ref.) | 1 | 1 | 1 | 1 |
| HR Q2 (95% CI) | 1.26, p = 0.162 (0.91–1.75) | 1.26, p = 0.261 (0.84–1.90) | 1.27, p = 0.310 (0.80–2.01) | 1.30, p = 0.308 (0.78–2.14) |
| HR Q3 (95% CI) | 1.55, p < 0.01** (1.12–2.14) | 1.41, p = 0.090 (0.94–2.09) | 1.62, p < 0.05* (1.03–2.53) | 1.40, p = 0.194 (0.84–2.30) |
| HR Q4 (95% CI) | 1.81, p < 0.001*** (1.32–2.48) | 1.40, p = 0.099 (0.93–2.09) | 1.32, p = 0.231 (0.83–2.08) | 0.98, p = 0.956 (0.58–1.70) |
| HR Ch (ref.) | 1 | 1 | 1 | 1 |
| G93ASOD1Ch (95% CI) | 2.99, p < 0.001*** (2.26–3.96) | 2.83, p < 0.001*** (2.03–3.95) | 2.89, p < 0.001*** (2.01–4.15) | 2.94, p < 0.001*** (1.97–4.40) |
n number of neurons, HR hazard ratio, Q1, Q2, Q3, Q4 quartiles of 5XUPRE levels, 95% CI 95% confidence interval, h hours, ref reference group. *p < 0.05, **p < 0.01, ***p < 0.001.