Table 4.

Top upstream regulators

Patient 1		Patient 2		Patient 3		Patient 4		Patient 5
Protein	P value	Protein	P value	Protein	P value	Protein	P value	Protein	P value
MAPT	1.32E−24	APP	5.03E−11	MAPT	7.78E−15	IL6	1.65E−16	MAPT	5.83E−12
APP	1.78E−22	MAPT	5.49E−11	APP	6.79E−13	APP	1.46E−14	APP	1.72E−11
TP53	3.21E−19	PSEN1	2.71E−09	TNF	8.03E−13	MAPT	2.12E−13	ZNF106	3.96E−11
TNF	9.00E−19	Growth hormone	2.87E−07	PSEN1	3.75E−12	PCGEM1	4.90E−12	PSEN1	6.04E−10
PSEN1	1.40E−17	MYC	7.50E−07	IL6	1.04E−11	TNF	5.37E−11	IL6	9.72E−10