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. 2020 May 20;11:957. doi: 10.3389/fmicb.2020.00957

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Copyright © 2020 Nagy, Vitális, Jakab, Borman, Forgács, Tóth, Majoros and Kovács.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic activity changes over time in case of biofilm formation in the presence of given farnesol concentrations (10–300 μM) for C. auris (A) and C. albicans (D), respectively. Metabolic activity changes over time in case of biofilm formation by farnesol pre-exposed cells (75 μM) in the presence of given farnesol concentrations (10–300 μM) for C. auris (B) and C. albicans (E), respectively. Metabolic activity changes over time for one-day-old preformed biofilms in the presence of given farnesol concentrations (10–300 μM) for C. auris (C) and C. albicans (F), respectively. Each time-point represents mean ± SEM (standard error of mean) of metabolic activity of clinical isolates (three independent experiments per isolate).