Table 1.
GCK-MODY prevalence in pregnant women with hyperglycemia.
| Authors | Selected cohort to test | Prevalence |
|---|---|---|
| Stoffel et al. (2) | 40 American women (different ethnicities) with GDM and a 1st-degree relative with diabetes | 5% |
| Zouali et al. (8) | 17 French women with GDM and familiarity for type 2 diabetes | 6% |
| Saker et al. (3) | 50 English women with GDM and persistent hyperglycemia | 6% |
| Ellard et al. (12) | 15 English Caucasian women with GDM and specific criteria (persistent fasting hyperglycemia >99 mg/dl, 2-h glycemic increase in OGTT <83 mg/dl, insulin therapy in pregnancy but not after pregnancy and fasting hyperglycemia or diabetes in at least one 1st-degree relative) | 80% |
| Kousta et al. (5) | 17 women (different ethnicities) with specific criteria (persistent fasting hyperglycemia >99 mg/dl, 2-h glycemic increase in postpartum OGTT <63 mg/dl) | 12% |
| Weng et al. (4) | 66 Swedish women with con GDM and familiarity for diabetes | 2% (3% other types of monogenic diabetes) |
| Zurawek et al. (6) | 119 Polish women with GDM and specific criteria (age <35 years, pregestational BMI <25 kg/m2, 2-h glycemic increase in OGTT <83 mg/dl, insulin therapy in pregnancy but not after pregnancy and fasting hyperglycemia or diabetes in at least one 1st-degree relative) | 9% |
| Chakera et al. (7) | 356 pregnant Anglo-Celtic women who performed OGTT | 1% |
| Sewell et al. (9) | 72 women with GDM | 0% |
| Rudland et al. (10) | 31 Australian women (different ethnicities) selected by Chakera pregnancy-specific criteria (7) | 12.9% |
| Gjesing et al. (11) | 354 Danish women with GDM treated with diet | 1.9% |