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. 2020 May 20;11:461. doi: 10.3389/fpsyt.2020.00461

Table 1.

Summary of Rome III Criteria on FGIDs.

Diagnostic criteria*
1. Functional dyspepsia Must include one or more of the following:
  • –Bothersome postprandial fullness,

  • –Early satiation,

  • –Epigastric pain and/or burning.


No evidence of structural disease (including at upper endoscopy) likely to explain the symptoms should be found.
1a. Epigastric pain syndrome (EPS) Must include all of the following:
  • –Pain or burning localized to the epigastrium of at least moderate severity, at least once a week,

  • –Intermittent character of pain/burning,

  • –Pain/burning should not be generalized or localized to other abdominal or chest regions,

  • –Pain/burning should not be relieved by defecation or passage of flatus.


Criteria for gallbladder and sphincter of Oddi disorders should not be fulfilled.
1b. Postprandial distress syndrome (PDS) Must include one or both of the following:
  • –Bothersome postprandial fullness, occurring after ordinary-sized meals, at least several times a week,

  • –Early satiation that prevents completing a regular meal, at least several times a week

2. Irritable bowel syndrome (IBS) Recurrent abdominal pain or discomfort** at least 3 days/month in the last 3 months associated with two or more of the following:
  • –Improvement with defecation,

  • –Onset associated with a change in frequency of stool,

  • –Onset associated with a change in form (appearance) of stool.

*Criteria fulfilled for the last 3 months with symptom onset at least 6 months prior to diagnosis.

**“Discomfort” stands for uncomfortable sensation, not described as pain.