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. 2020 May 26;11(3):e00932-20. doi: 10.1128/mBio.00932-20

TABLE 2.

Data sets of P. aeruginosa clinical isolates were analyzed to reveal gene and residue-level parallelism within the aminoglycoside resistance loci observed in this study

Study authors (reference) Variants
fusA1 ptsP
López-Causapé et al. (58) V93A, K430E, N482S, K504E, Y552C,
P554L, D588G, P618L, T671Ia
Markussen et al. (60) G118S, D467G L42L, R61H
Chung et al. (57) A418T, V538A, G610V, Q678Ra
Bolard et al. (24) V93A, A555E, T671Aa
a

Mutations at this amino acid position occurred in populations treated with TOB in this study.