Table 2.
Time to clinically meaningful response for patients on the seven most frequently used drugs (independently or in combination with other treatments)
| Treatment (N) | N studies | N patients | % of patients on drug extractable TCMR | Mean (SD) TCMR | Standard error |
|---|---|---|---|---|---|
| Antivirals for systemic use | |||||
| Lopinavir/ritonavir | |||||
| Total | 15 | 76 | 3.8% | 11.7 (1.09) | 0.13 |
| Patient-level | 14 | 25 | |||
| Summary-level | 1 | 51 | |||
| Umifenovir | |||||
| Total | 10 | 13 | 1.3% | 10.9 (7.78) | 2.16 |
| Patient-level | 10 | 13 | |||
| Summary-level | 0 | 0 | |||
| Oseltamivir | |||||
| Total | 10 | 10 | 1.1% | 19.8 (10.62) | 3.36 |
| Patient-level | 10 | 10 | |||
| Summary-level | 0 | 0 | |||
| Immunostimulants | |||||
| Interferon-α/β | |||||
| Total | 14 | 107 | 6.1% | 9.9 (2.65) | 0.26 |
| Patient-level | 12 | 32 | |||
| Summary-level | 2 | 75 | |||
| Corticosteroids for systemic use | |||||
| Methylprednisolone | |||||
| Total | 12 | 13 | 3.1% | 14.2 (6.69) | 1.86 |
| Patient-level | 12 | 13 | |||
| Summary-level | 0 | 0 | |||
| Antibacterials for systemic use | |||||
| Moxifloxacin | |||||
| Total | 10 | 10 | 1.7% | 16.2 (8.6) | 2.73 |
| Patient-level | 10 | 10 | |||
| Summary-level | 0 | 0 | |||