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. 2020 May 27;9(3):435–449. doi: 10.1007/s40121-020-00303-8

Table 2.

Time to clinically meaningful response for patients on the seven most frequently used drugs (independently or in combination with other treatments)

Treatment (N) N studies N patients % of patients on drug extractable TCMR Mean (SD) TCMR Standard error
Antivirals for systemic use
Lopinavir/ritonavir
 Total 15 76 3.8% 11.7 (1.09) 0.13
  Patient-level 14 25
  Summary-level 1 51
Umifenovir
 Total 10 13 1.3% 10.9 (7.78) 2.16
  Patient-level 10 13
  Summary-level 0 0
Oseltamivir
 Total 10 10 1.1% 19.8 (10.62) 3.36
  Patient-level 10 10
  Summary-level 0 0
Immunostimulants
Interferon-α/β
 Total 14 107 6.1% 9.9 (2.65) 0.26
  Patient-level 12 32
  Summary-level 2 75
Corticosteroids for systemic use
Methylprednisolone
 Total 12 13 3.1% 14.2 (6.69) 1.86
  Patient-level 12 13
  Summary-level 0 0
Antibacterials for systemic use
Moxifloxacin
 Total 10 10 1.7% 16.2 (8.6) 2.73
  Patient-level 10 10
  Summary-level 0 0