Table 2. The prognostic significance of SERPINB5 mRNA in non-small lung cancer by Kaplan–Meier plotter.
Clinicopathological features | OS | PFS | ||
---|---|---|---|---|
HR | P | HR | P | |
Sex | ||||
Male | 1.69 (1.41–2.03) | 9.40E-09 | 1.59 (1.21–2.09) | 8.20E-04 |
Female | 1.55 (1.23–1.96) | 1.90E-04 | 1.32 (0.94–1.87) | 1.10E-01 |
Smoking | ||||
Yes | 1.7 (1.38–2.09) | 3.90E-07 | 1.49 (1.12–1.97) | 5.60E-03 |
No | 2.23 (1.27–3.89) | 3.90E-03 | 1.83 (1.13–2.96) | 1.30E-02 |
Histology | ||||
Adenocarcinoma | 1.88 (1.49–2.38) | 7.10E-08 | 1.96 (1.44–2.68) | 1.60E-05 |
Squamous | 0.79 (0.617–1.03) | 8.10E-02 | 1.68 (0.97–2.9) | 6.10E-02 |
T | ||||
1 | 1.71 (1.28–2.3) | 2.80E-04 | 1.49 (0.81–2.75) | 2.00E-01 |
2 | 1.53 (1.17–1.99) | 1.70E-03 | 0.82 (0.6–1.11) | 1.90E-01 |
3 | 0.66 (0.37–1.19) | 1.67E-01 | 0.62 (0.22–1.76) | 3.60E-01 |
4 | 0.64 (0.34–1.23) | 1.80E-01 | ||
N | ||||
0 | 1.53 (1.24–1.89) | 7.50E-05 | 1.31 (0.91–1.87) | 1.40E-01 |
1 | 1.37 (1–1.87) | 5.00E-02 | 0.74 (0.47–1.17) | 1.90E-01 |
2 | 1.48 (0.91–2.41) | 1.10E-01 | 2.73 (1.22–6.09) | 1.10E-02 |
TNM stage | ||||
I | 2.08 (1.59–2.72) | 4.80E-08 | 2.05 (1.31–3.2) | 1.30E-03 |
II | 1.23 (0.86–1.78) | 2.60E-01 | 0.4 (0.22–0.73) | 1.70E-03 |
III | 0.76 (0.43–1.34) | 3.40E-01 | ||
Chemotherapy | ||||
Yes | 2.41 (1.58–3.68) | 2.60E-05 | 1.66 (1.08–2.57) | 2.00E-02 |
No | 2.26 (1.62–3.17) | 1.00E-06 | 1.57 (1.03–2.37) | 3.30E-02 |
Radiotherapy | ||||
Yes | 3.94 (2.2–7.05) | 9.30E-07 | 2.16 (1.24–3.78) | 5.70E-03 |
No | 1.76 (1.22–2.53) | 2.00E-03 | 1.37 (0.89–2.12) | 1.50E-01 |
Surgery success | ||||
Surgical margins negative | 2.25 (1.79–2.84) | 1.40E-12 | 1.85 (1.39–2.46) | 2.20E-05 |