Figure 5. Overexpression of HOTAIR heightened cell viability, curbed apoptosis and oxidative damage, while these effects were reversed by miR-106b-5p in H₂O₂-induced cardiomyocytes.

(A–G) NC, HOTAIR, HOTAIR + miR-NC or HOTAIR + miR-106b-5p into H9c2 cells were transfected into H9c2 cells induced by H₂O₂. (A) The level of miR-106-5p was examined by qRT-PCR. (B) The cell viability was measured by CCK-8. (C) Flow cytometry was employed to detect cell apoptosis in vitro. (D) Western blot assay was aimed to examine apoptosis-relative proteins expression. The level of LDH and SOD were identified by ELISA; *P<0.05.