Table 1.

Demographics, seizure semiology, EEG and neuroimaging of patients with eating epilepsy

No.	Age (years)	Sex	Age of onset (years)	Trigger stimuli	Triggering meal	Seizure semiology	Type of seizures	Seizure frequency before clobazam (per week)	Family history	EEG	Neuroimaging (MRI brain)
1	24	M	15	Eating	L, D	Aura-Vague uneasiness; Ictus-Sudden onset staring followed by manual automatisms and ictal speech.	Focal onset impaired awareness	7–14	None	Frequent left posterior temporal IEDs with secondary generalization	Normal
2	28	M	21	Eating	L, D	Aura-None; Ictus-Sudden unresponsiveness for few seconds associated oromandibular automatisms sometimes is followed by posturing of all limbs	Focal onset impaired awareness, focal to bilateral tonic clonic	7–14	None	Normal	Right temporal sclerosis
3	22	M	10	Eating	L, D	Aura-None; Ictus-Behavioral arrest followed by eyes to one side and posturing of both upper limbs (right>left). Sometimes clonic movement in fingers.	Focal to bilateral tonic clonic	5–7	None	Normal	Bilateral perisylvian gliosis
4	19	M	8	Eating	Any	Aura-Giddiness; Ictus-Fall, tonic posturing of limbs with salivation. Followed by prolonged sleepiness.	Generalized tonic	14–21	None	Left centro-temporal IEDs	Left inferior frontal gliosis
5	14	M	Birth	Eating, anxiety	Any meal, Fluids	Aura-None; Ictus-Sudden onset stare with behavior arrest followed by subtle tonic posturing of limbs with neck deviation for few seconds.	Focal to bilateral tonic clonic	21–28	None	Bilateral peri-rolandic spike	Bilateral perisylvian gliosis (left>right)
6	31	M	27	Eating, spontaneous	Any	Aura-None; Ictus-Sudden onset unresponsiveness, stare, not able to talk for 1–2 minutes.	Focal onset impaired awareness	1	None	Right posterior head region and left temporal spikes	Normal
7	27	F	12	Eating	L, D	Aura-Epigastric rising sensation, heaviness in head; Ictus-Behavioral arrest wit spontaneous recovery in lass than a minute, sometimes develops tonic clonic movements of right UL/LL followed by all 4 limbs; post ictal weakness of right UL for about 5–10 minutes.	Focal onset impaired awareness, focal to bilateral tonic clonic	1	None	Normal	Normal
8	22	M	12	Eating	Any	Aura-None; Ictus-Sudden staring look. Oro-mandibular automatisms for about few seconds followed by headache and sleep. Occasionally progresses to generalized seizures with tonic clonic movements.	Focal onset impaired awareness, focal to bilateral tonic clonic	0.5–1	None	Normal	Normal
9	51	M	31	Eating	Any	Aura-Cephalic sensation; Ictus-Behavioral arrest, stare, spontaneously recovers to normal in 30–40 seconds. No post ictal confusion.	Focal onset impaired awareness	2–3	None	Normal	Normal
10	25	M	25	Eating, bathing	L, D	Aura-None; Sudden ill-defined uneasiness, some involuntary movements over the jaw region with restlessness for few seconds followed by loss of consciousness for 1–2 minutes. Sleeps thereafter.	Focal onset impaired awareness	0.5	None	Normal	Right frontal perisylvian sclerosis
11	24	M	11	Eating	L, D	Aura-None. Will complain of sudden sleepiness during later part of meals and will doze off for one minute. Rare episodes of GTCS in past.	Focal onset impaired awareness, Focal to bilateral tonic clonic	3–4	None	Right centro-temporal IEDs	Normal
12	21	M	18	Eating	L, D	Aura-None. Suddenly feels headache, uneasiness followed by staring look lasting for 40–50 seconds. Sometimes induces vomiting for relief from uneasiness. Rare episodes progressing to bilateral tonic clonic movements with post ictal confusion.	Focal onset impaired awareness, focal to bilateral tonic clonic	4–7	None	Rare bilateral post head region IEDs	Normal

EEG, electroencephalogram; MRI, magnetic resonance imaging; M, male; L, lunch; D, dinner; IEDs, interictal epileptiform discharges; F, female; GTCS, generalized tonic-clonic seizures.