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. 2020 May 13;13:100226. doi: 10.1016/j.ynstr.2020.100226

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Differential brain c-fos activation pattern obtained through comparisons between the drug-pretreated groups and the Vehicle-SPS group. (A) Scatter plot showing the relationship between the z-scores for each brain region in the Vehicle-SPS versus Vehicle-Sham (x-axis) and ACH-000029-SPS versus Vehicle-SPS (y-axis) comparisons. (B) Scatter plot showing the relationship between the z-scores for each brain region in the Vehicle-SPS versus Vehicle-Sham (x-axis) and Prazosin-SPS versus Vehicle-SPS (y-axis) comparisons. Brain areas upregulated in the Vehicle-SPS group but downregulated in the drug-pretreated groups are represented as green circles. Regions downregulated in the Vehicle-SPS but upregulated in the drug-pretreated groups are displayed as red circles. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)