Figure 3. Estimates of C-Reactive Protein on a Log Scale From Generalized Estimating Equations Analysis by Treatment Assignment.

The difference between doxycycline and placebo in slope per year is −0.089 (95% CI, −0.161 to −0.016; P = .002) for log(C-reactive protein), mg/L. Open circles represent mean values; lines in the boxes, medians; the box ends, interquartile ranges; and lines spanning boxes, slope.