Table 1.
Baseline characteristics, pathological findings and outcomes in the whole population of patients stratified by RDW level and their correlation with RDW.
Whole population n = 74 |
RDW |
|||
---|---|---|---|---|
Low (<13.5%) n = 28 |
High (≥13.5%) n = 46 |
p-value | ||
Sex (% of males) | 79,73% | 82,14% | 78,26% | 0.69 |
Age [years] | 60,7 (40.7−83.0) | 59,8 (49.6−76.4) | 61,2 (40.7−83.0) | 0.47 |
RDW [%] | 13.9 (12.0−16.3) | 12,8 (12,0−13.4) | 14,5 (13.5−16.3) | |
Hemoglobin [g/dl] | 13.8 (10.3−18.5) | 14.0 (11.0−15.9) | 13.7 (10.3−18.5) | 0.23 |
Hematocrit [%] | 40,3 (30.8−54.6) | 41,2 (33.1−47.2) | 39.8 (30.8−54.6) | 0.1 |
RBC (106/mm3) | 4.38 (3.56−5.64) | 4.43 (3.68−5.21) | 4.35 (3.56−5.64) | 0.31 |
WBC (103/mm3) | 8.3 (5−15) | 8.2 (5.4−14.5) | 8.4 (5−15) | 0.86 |
TNM T stage | 0.84 | |||
1 | 2.7% | 3.6% | 2.2% | |
2 | 24.3% | 17.8% | 28.3% | |
3 | 18.9% | 25% | 15.2% | |
4 | 54.1% | 53.6% | 54.3% | |
TNM N stage | 0.37 | |||
0 | 25.7% | 28.6% | 23.9% | |
1 | 18.9% | 25% | 15.2% | |
2 | 47.3% | 39.3% | 52.2% | |
3 | 8.1% | 7.1% | 8.7% | |
Tumor volume | 0.5 | |||
<15cc | 28.4% | 28.6% | 28.3% | |
15−30cc | 31.1% | 35.7% | 28.3% | |
>30cc | 40.5% | 35.7% | 43.4% | |
% base of tongue | 75.7% | 78.6% | 73.9% | 0.65 |
Concomitant diseases | 58.1% | 50% | 62% | 0.30 |
History of smoking | 0.29 | |||
Non-smoker | 11% | 17.9% | 6.7% | |
Former smoker | 6.8% | 7.1% | 6.7% | |
Active smoker | 82.2% | 75% | 86.6% | |
Pack-years | 32.5 (0−105) | 27.6 (0−90) | 35.6 (0−105) | 0.07 |
History of alcohol abuse | 17.8% | 17.9% | 17.8% | 0.99 |
ZUBROD | 0.97 | |||
0−1 | 93,2 | 89,3% | 95,6% | |
2 | 5.4% | 10.7% | 2.2% | |
3+ | 1.4% | 0% | 2.2% | |
Fractionation regimen: | 0.01 | |||
Conventional | 48.6% | 64.3% | 39.1% | |
CAIR31 | 27% | 28.6% | 26.1% | |
CHA-CHA32 | 19% | 7.1% | 26.1% | |
EBRT + BT | 5.4% | 0% | 8.7% | |
Addition of chemotherapy | 27% | 36% | 22% | 0.19 |
Type of chemotherapy | 0.12 | |||
Neoadjuvant | 25% | 20% | 30% | |
Concomitant | 40% | 40% | 40% | |
Both | 35% | 40% | 30% | |
5-year OSa | 42% | 67% | 26% | 0,0005 |
Continuous variables are presented as mean (min-max range) unless indicated otherwise. Dichotomous variables are presented as percentages.
log-rank.