Table 3.

RADREMI study calendar.

	Baseline Screening	SRS (stereotactic radiosurgery)	1 Month Follow Upa	3 Month Follow Upa	6 Month Follow Upa	9 Month Follow Upa	12 Month Follow Upb
	Within 30 days of SRS	Gamma Knife or Linear Accelerator (LINAC)	30 days post SRS	90 days post SRS	180 days post SRS	270 days post SRS	1 years post SRS
Radiation Oncology consult and consent	X
Medical History (including dexamethasone usage)	X		X	X	X	X	X
Physical Examination	X		X	X	X	X	X
Vitals	X	X	X	X	X	X	X
ds-GPA/ECOG performance status/KPS	X		X	X	X	X	X
Diagnostic MRI Brain	X
MRI Brain Planning Scand		X
ALC, WBC, Hgb, platelets	X
Toxicity assessment			X	X	X	X	X
MRI Brain with and without contrastc			X	X	X	X	X

^aVariations of +/- 14 days from the scheduled visit are permitted.

^bAfter 12-months post-SRS, subjects will be followed at physician’s discretion, approximately every 3-6 months per standard of care. Any MRI Brain, physical exam or vitals obtained at these appointments will be gathered. However, if these procedures are not performed per standard of care, this will not be a deviation.

^cMRI Brain performed at Indiana University will have sequences including contrast, no contrast, FLAIR, DTI and PWI. If patient receives MRI Brain outside of Indiana University, a minimum of contrast, no contrast and FLAIR will need to be obtained and all sequences mentioned above are encouraged.

^dVariations of -30 days from the scheduled visit are permitted for linear accelerator based SRS, and may include the baseline screening MRI at the treating radiation oncologist’s discretion.