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Tumor growth curves revealing the comparison of control and chemotherapy groups. PDX mice in the chemotherapy group were treated with GEM or GEM + nab-PTX until the tumor volume was 1,500 mm3 or more. Although there were PDX lines with high and low chemo-sensitivity, all became chemo-resistant eventually, and an increase in the tumor volume was also observed in the chemotherapy group. PDX, patient-derived xenograft; GEM, gemcitabine; nab-PTX, nab-paclitaxel.
