Table III.
Association between cytoplasmic RBMS3 expression and clinicopathological variables (n=125).
| Cytoplasmic RBMS3 expression | ||||
|---|---|---|---|---|
| Clinicopathological variables | Total | Positive | Negative | P-value |
| Sex | 0.182 | |||
| Male | 34 | 16 (47.1) | 18 (52.9) | |
| Female | 91 | 31 (34.1) | 60 (65.9) | |
| Age (years) | 0.417 | |||
| <68 | 58 | 24 (41.4) | 34 (58.6) | |
| ≥68 | 67 | 23 (34.3) | 44 (65.7) | |
| Tumor size (cm) | 0.344 | |||
| <2 | 60 | 20 (33.3) | 40 (66.7) | |
| ≥2 | 65 | 27 (41.5) | 38 (58.5) | |
| Differentiation | 0.023 | |||
| High/moderate | 80 | 36 (45) | 44 (55) | |
| Low/undifferentiated | 45 | 11 (24.4) | 34 (75.6) | |
| Depth of invasion | 0.972 | |||
| T1/T2 | 37 | 14 (37.8) | 23 (62.2) | |
| T3/T4 | 88 | 33 (37.5) | 55 (62.5) | |
| Lymph node metastasis | 0.007 | |||
| Yes | 51 | 12 (23.5) | 39 (76.5) | |
| No | 74 | 35 (47.3) | 39 (52.7) | |
| TNM | 0.004 | |||
| I/II | 81 | 38 (46.9) | 43 (53.1) | |
| III/IV | 44 | 9 (20.5) | 35 (79.5) | |
| Gallstones | 0.757 | |||
| Yes | 83 | 32 (38.6) | 51 (61.4) | |
| No | 42 | 15 (35.7) | 27 (64.3) | |
| AFP (µg/l) | 0.193 | |||
| <20 | 120 | 47 (39.2) | 73 (60.8) | |
| ≥20 | 5 | 0 (0) | 5 (100) | |
| CEA (ng/ml) | 0.419 | |||
| <5 | 99 | 39 (39.4) | 60 (60.6) | |
| ≥5 | 26 | 8 (30.8) | 18 (69.2) | |
| CA199 (U/ml) | 0.342 | |||
| <37 | 81 | 28 (34.6) | 53 (65.4) | |
| ≥37 | 44 | 19 (43.2) | 25 (56.8) | |
P<0.05 was defined as statistically significant and is indicated in bold. RNA binding motif, single-stranded interacting protein 3; TNM, tumor-node-metastasis; AFP, alpha fetoprotein; CEA, carcino-embryonic antigen; CA199, carbohydrate antigen 199.