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. 2020 May 27;21:130. doi: 10.1186/s12931-020-01372-6

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Collagen III expression in lung tissue and its immunohistochemical scores

The figure demonstrates a representative view (× 100) from each group. Each bar represents the mean ± SD. The LPS group showed deepest staining, indicating that collagen III expression was significantly increased. Following with SN50 intervention, collagen III expression decreased obviously and the staining faded. ^ap<0.05 compared with Control. ^bp<0.05 compared with N-SN50. ^cp<0.05 compared with LPS. ^dp<0.05 compared with L-SN50. ^ep<0.05 compared with M-SN50. (A, Control group; B, N-SN50; C, LPS group; D, L-SN50, E, M-SN50, F, H-SN50).