Table 5:

Fold changes of the mRNA levels of the stress inducible-genes in aging male mouse liver.

non-genotoxic stress-inducible genes		Fold change (24 vs. 6 month)
Name	Description	WT	RXRα deficiency
HSPA8	heat shock 70kDa protein 8	−2.04	(-)
HSP90B1	heat shock protein 90kDa beta, member 1	−2.39	−2.19
DNAJB4	DnaJ (Hsp40) subfamily B, member 4	−2.40	(-)
HYOU1	hypoxia up-regulated 1	−2.56	−3.65
HSPB8	heat shock 22kDa protein 8	−3.22	−2.11
HSP90AA1	heat shock protein 90kDa alpha	−4.79	−3.18
HSPB1	heat shock 27kDa protein 1	−6.41	−4.91
DNAJB1	DnaJ (Hsp40) subfamily B, member 1	−27.10	−2.13
HSPA1B	heat shock 70kDa protein 1B	−28.01	−3.94
HSPA1A	heat shock 70kDa protein 1A	−44.84	(-)
genotoxic stress-inducible genes		Fold change (24 vs. 6 month)
Name	Description	WT	RXRα deficiency
OSGIN1	oxidative stress induced growth inhibitor 1	3.24	2.10
DDIT3	DNA-damage-inducible transcript 3	−2.24	(-)
GADD45G	growth arrest and DNA-damage, gamma	−3.61	−2.91
GADD45A	growth arrest and DNA-damage alpha	−4.43	−4.91
ATF3	activating transcription factor 3	−33.01	(-)