Table 4.
Fungal dysbiosis in complications associated with liver cirrhosis.
| Authors | Population | N | Comparison | Implicated microbiota |
Methodology | ||
|---|---|---|---|---|---|---|---|
| Phylum | Family | Genus | |||||
| Bajaj et al.85 | Outpatients cirrhotics | 77 | Inpatients vs Outpatients | Basidiomycota↓ Ascomycota |
Bacteroidetes/Ascomycota ratio ↑ Saccharomycetaceae |
N/A Candida↑ |
Metagenomics (Stool sample) |
| Inpatients cirrhotics | 66 | After antibiotics vs before antibiotics | Ascomycota | Saccharomycetaceae | Candida↑ | ||
| Controls | 26 | Inpatients vs Outpatients | Ascomycota | Saccharomycetaceae | Candida↑ | ||
| Proteobacteria | Enterobacteriaceae↑ | N/A | |||||
| Firmicutes | Enterococcaceae↑ | N/A | |||||
| Outpatients vs Controls | Basidiomycota↓ | N/A | N/A | ||||
| Ascomycota | Saccharomycetaceae | Candida↑ | |||||
| Inpatients vs Controls | Proteobacteria | Enterobacteriaceae ↑ | N/A | ||||
| Firmicutes | Enterococcaceae↑ | N/A | |||||
| Outpatients on antibiotics | Ascomycota ↑ | Saccharomycetaceae | Candida↑ | ||||
| Proteobacteria | Pasteurellaceae↑ | N/A | |||||
| Yang et al.86 | Healthy individuals | 8 | Patients vs Healthy individuals | Ascomycota | Saccharomycetaceae | Candida↑ | lllumina MiSeq platform |
| Alcohol-dependent | 10 | sequencing of the V4 region of 16S rRNA (Stool sample) | |||||
| patients (nonprogressive liver disease) | |||||||
| Patients with alcoholic liver cirrhosis | 4 | ||||||
Comparison of condition A vs condition B:
↑
signifies an increase in condition A relative to condition B.
↓
signifies a decrease in condition A relative to condition B.
Abbreviation: N/A, not applicable.