Table 2.
Functions of Th9 cells and1 IL-9 on different tumors.
| System | Type of cancers | Role of Th9 cells or IL-9 | References |
|---|---|---|---|
| Hematologic | B-cell non-Hodgkin's lymphoma (NHL) | (99–105) | |
| Chronic lymphocytic leukemia (CLL) | |||
| T-cell leukemia(ACTL) | |||
| Hodgkin lymphoma(HD) | Pro-tumor (IL-9) | ||
| Cutaneous T-Cell Lymphoma (CTCL) | |||
| Anaplastic large-cell lymphoma (ALCL) | |||
| NKT cell lymphoma | |||
| Digestive system | Hepatocellular carcinoma | Pro-tumor (Th9) | (106) |
| Colon cancer | Anti-tumor (Th9) | (85, 107, 108) | |
| Dermal system | Melanoma | Anti-tumor (Th9) | (10, 27, 28, 91, 107, 109–111) |
| Respiration system | Lung cancer | Pro/anti-tumor (Th9) | (106) |
| (76, 112) | |||
| Reproductive System | Breast cancer | Anti-tumor (Th9) | (113) |
NHL, B-cell non-Hodgkin's lymphoma; CLL, chronic lymphocytic leukemia; ALCL, Anaplastic large-cell lymphoma; CTCL, Cutaneous T-cell lymphoma; HD, Hodgkin lymphoma; ATCL, T-cell leukemia.