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Comparison of human predicted Rt with observes Rt in rats.
| Item | Lung |
Heart | Liver | Kidney | ||||
|---|---|---|---|---|---|---|---|---|
| Right top lobe | Right middle lobe | Right low lobe | Left top lobe | Left low lobe | ||||
| Tissue half-life (day) | 29.7 | 38.1 | 22.2 | 25.2 | 22.2 | 24.5 | 33.0 | 25.0 |
| Predicted ratio in human | 3.79 | 4.86 | 2.83 | 3.21 | 2.84 | 3.13 | 4.22 | 3.19 |
| Obvious ratio in rat | 4.89 | 4.89 | 4.89 | 4.89 | 4.89 | 3.56 | 2.90 | 3.34 |
| Ratio | 0.77 | 0.99 | 0.58 | 0.66 | 0.58 | 0.88 | 1.46 | 0.96 |
Abbreviations: Rt ratio of tissue half-life to plasma half-life.
