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. 2020 May 19;11:425. doi: 10.3389/fphys.2020.00425

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Copyright © 2020 Yang, Wang, Zhang, Cai, Jiang, Zha and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Met prevented diabetes-induced cardiomyocyte apoptosis. (A) TUNEL staining. (B) Immunohistochemical staining for Bax. (C) Immunohistochemical staining for Bcl-2. (D) Analysis of TUNEL-positive cells. (E) Images of Bcl-2 and Bax protein levels. (F) Analysis of Bax. (G) Analysis of Bcl-2. (H) Analysis of the Bax/Bcl-2 ratio. The data are mean ± SEM; * P value less than 0.05 versus the control group; ^# P value less than 0.05 versus the DM group; n = 3–5 per group.