TABLE 2.
Met improved general features and echocardiographic properties in DM mice.
| Parameter | control | DM | DM-Met |
| HW (mg) | 144.9 ± 2.8 | 99.9 ± 6.3* | 111.6 ± 4.9* |
| HW/BW (mg/g) | 4.6 ± 0.1 | 5.2 ± 0.2* | 4.0 ± 0.2*# |
| HR (bpm) | 505.21 ± 36.84 | 372.71 ± 34.22* | 462.25 ± 6.24 |
| LVPWD (mm) | 0.68 ± 0.06 | 0.72 ± 0.04 | 0.58 ± 0.01 |
| LVIDD (mm) | 3.38 ± 0.12 | 3.57 ± 0.06 | 3.43 ± 0.05 |
| LVEF (%) | 72.13 ± 3.17 | 58.31 ± 4.18* | 71.32 ± 2.64# |
| LVFS (%) | 40.64 ± 2.66 | 30.37 ± 2.75* | 39.72 ± 2.24# |
HR, heart rate; LVPWD, left ventricular posterior wall thickness; LVIDD, left ventricular internal dimension in end-diastole; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening. The data are mean ± SEM; *P value less than 0.05 versus the control group; #P value less than 0.05 versus the DM group; n = 4–11 per group.