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(A-C) DUB inhibitor structures. (D and E) Time course of cell proliferation and adhesion treated with DMSO (control), RA-9 (5 µM), PR-619 (10 µM) and LDN-91946 (10 µM) measured by resistance at 4 kHz; (D) A549 cells; (E) H2373 cells. DUB, deubiquitinating enzyme.
