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. 2020 Apr 3;57(1):183–196. doi: 10.3892/ijo.2020.5038

Figure 8.

Figure 8

Chemical structure of CVB-D and its inhibitory mechanism in CRC. (A) Chemical structure and 3D structure of CVB-D. (B) The molecular mechanism of CVB-D-induced inhibition of CRC occurs via the CTHRC1-AKT/ERK-Snail signaling pathway. CVB-D, cyclovirobuxine D; CTHRC1, collagen triple helix repeat containing 1; CRC, colorectal cancer.