Table 2.
Tonic GABAA conductances reduce the ΔVm and Ca2+ transient induced by EPSP burst to a greater extent than those induced by bAP/EPSP pairing in the model neurona
| GABA | APV | GABA + APV | |
|---|---|---|---|
| bAP/EPSP pairing | |||
| Dendrite ΔVm AUC | 73.3 ± 0.4% (6) | 87.5 ± 1.2% (6) | 73.3 ± 0.7% (6) |
| Peak Δ[Ca2+]i | 76.7 ± 1.8% (6) | 6.8 ± 0.7% (6) | 5.6 ± 0.5% (6) |
| EPSP burst | |||
| Dendrite ΔVm AUC | 48.8 ± 1.1% (6) | 66.2 ± 0.2% (6) | 44.6 ± 0.9% (6) |
| Peak Δ[Ca2+]i | 53.8 ± 0.9% (6) | 7.6 ± 0.6% (6) | 0.0 ± 0.0% (6) |
aData are mean ± SEM (n). The responses were normalized to control. GABA, the introduction of the tonic GABAA conductance; APV, removal of NMDAR conductance; GABA + APV, both.