Figure 1.

Study design. All animals were implanted with a spinal cord window and allowed to recover for up to 5 d. After the recovery period, animals underwent 3 d of baseline pain testing (von Frey hairs and Hargreaves test). Baseline imaging session was done before and on the same day as SNI. Pain testing and imaging occurred on 3 and 7 d after SNI. N values indicate the number of neurons sampled in each group. Neurons sampled for baseline to day 3, and baseline to day 7, were separate groups.