Table 5.
Subgroup | HR | 95% CI | P |
---|---|---|---|
OS | |||
CD28 vs 4-1BB | 0.609 | 0.254-1.461 | .267 |
With vs without EMD | 0.455 | 0.196-1.056 | .067 |
No previous transplant vs posttransplant relapse | 2.184 | 0.830-5.744 | .113 |
BM blasts ≤20% vs >20% | 2.968 | 1.270-6.901 | .012* |
TP53+ mutation vs TP53– mutation | 0.189 | 0.073-0.488 | .001† |
CAR T-cell bridged into allo-HSCT vs CAR T-cell therapy alone | 12.250 | 4.774-31.438 | <.001† |
LFS | |||
CD28 vs 4-1BB | 0.927 | 0.351-2.452 | .879 |
Without vs with EMD | 1.192 | 0.455-3.123 | .720 |
No previous transplant vs posttransplant relapse | 2.881 | 0.939-8.837 | .064 |
BM blasts ≤20% vs >20% | 1.569 | 0.610-4.039 | .350 |
TP53+ mutation vs TP53– mutation | 0.279 | 0.092-0.849 | .025* |
CAR T-cell bridged into allo-HSCT vs CAR T-cell therapy alone | 26.430 | 7.292-95.793 | <.001† |
P < .05.
P < .01.