Response with blinatumomab in R/R B-cell ALL (N = 227) |
|
CR + CRi |
149 (67) |
CR with MRD−
|
109 (49) |
CR with MRD+
|
37 (17) |
CRi |
3 (1) |
Partial remission |
8 (4) |
Nonevaluable |
4 (2) |
CR + CRi in Ph+ (n = 55) |
41 (74.5) |
CR + CRi in primary refractory (n = 55) |
35 (64) |
CR + CRi after salvage 1 (n = 126) |
90 (71) |
CR + CRi after salvage 2 (n = 51) |
33 (65) |
CR + CRi after early relapse (<18 months of first remission) (n = 121) |
78 (64) |
CR + CRi after late relapse (≥36 months of first remission) (n = 17) |
12 (71) |
Response to EMD (n = 10) |
2 (20) |
Response with blinatumomab in B-cell ALL with MRD (n = 12) |
No. of patients who achieved MRD−
|
9 (75) |